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Article

Molecular etiology of second primary tumors in contralateral tonsils of human papillomavirus-associated index tonsillar carcinomas.

Oral oncology - 1 Mar 2013

Joseph Andrew W, Ogawa Takenori, Bishop Justin A, Lyford-Pike Sofia, Chang Xiaofei, Phelps Timothy H, Westra William H, Pai Sara I

Abstract excerpt

OBJECTIVES: For patients with tobacco-related head and neck squamous cell carcinoma (HNSCC), the occurrence of a second primary tumor (SPT) is an ominous development that is attributed to a field cancerization effect and portends a poor clinical outcome. The goal of this study was to determine whether patients with human papillomavirus (HPV)-related index tonsillar carcinomas can also develop SPTs in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23062994
DOI: 10.1016/j.oraloncology.2012.09.009
PMCID: PMC3548989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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