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Article

Is BRAF mutation associated with lymph node metastasis in patients with papillary thyroid cancer?

Surgery - 1 Dec 2012

Lee Kathleen C, Li Carol, Schneider Eric B, Wang Yongchun, Somervell Helina, Krafft Matthew, Umbricht Christopher B, Zeiger Martha A

Abstract excerpt

BACKGROUND: Some have proposed using V600E BRAF mutation status to dictate the surgical management of patients with papillary thyroid cancer (PTC). However, well-designed studies examining BRAF association with aggressive clinicopathologic features of PTC, including the presence of lymph node metastases (LNM), in patients who have undergone routine central lymph node dissection (CLND), are lacking. METHODS: Under...

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Share to Carcinoma, Papillary
Share to Lymph Node Excision

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphatic Metastasis

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Share to Proto-Oncogene Proteins B-raf

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Source

Open in PubMed Open full text

Identifiers

PMID: 23062653
DOI: 10.1016/j.surg.2012.08.019
PMCID: PMC3715093

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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