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Article

BRAF V600E mutation independently predicts central compartment lymph node metastasis in patients with papillary thyroid cancer.

Annals of surgical oncology - 1 Jan 2013

Howell Gina M, Nikiforova Marina N, Carty Sally E, Armstrong Michaele J, Hodak Steven P, Stang Michael T, McCoy Kelly L, Nikiforov Yuri E, Yip Linwah

Abstract excerpt

PURPOSE: This study was designed to examine whether available preoperative clinical parameters, including B-type Raf kinase (BRAF) V600E mutation status, can identify patients at risk for central compartment lymph node metastasis (CLNM). METHODS: Under an institutional review board-approved protocol, we conducted a single-center, retrospective review of all patients who had initial thyroidectomy for histologic...

Read the complete abstract on PubMed

Topics

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Share to Biopsy, Fine-Needle
Share to Carcinoma, Papillary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Logistic Models

Share to Lymph Nodes

Share to Lymphatic Metastasis

Share to Multivariate Analysis

Share to Proto-Oncogene Proteins B-raf

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 22941165
DOI: 10.1245/s10434-012-2611-0

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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BRAF V600E mutation independently predicts central compartment lymph node metastasis in patients with papillary thyroid cancer.PMID 22941165Read ↗

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