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Article

Carriers of the fragile X mental retardation 1 (FMR1) premutation allele present with increased levels of cytokine IL-10.

Journal of neuroinflammation - 13 Oct 2012

Marek Diana, Papin Stephanie, Ellefsen Kim, Niederhauser Julien, Isidor Nathalie, Ransijn Adriana, Poupon Lucienne, Spertini Francois, Pantaleo Giuseppe, Bergmann Sven, Beckmann Jacques S, Jacquemont Sebastien, Tanackovic Goranka

Abstract excerpt

BACKGROUND: Fragile X-associated tremor/ataxia syndrome (FXTAS) is an inherited late-onset neurodegenerative disorder, characterized both by neurological and cognitive deficits. It is caused by the expansion of CGG repeats (55 to 200 repeats) in the noncoding region of the fragile X mental retardation 1 (FMR1) gene. Abnormal immunological patterns are often associated with neurodegenerative disorders and...

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Source

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Identifiers

PMID: 23062006
DOI: 10.1186/1742-2094-9-238
PMCID: PMC3528457

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Carriers of the fragile X mental retardation 1 (FMR1) premutation allele present with increased levels of cytokine IL-10.PMID 23062006Read ↗

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