Article
CNTF receptor subunit α as a marker for glioma tumor-initiating cells and tumor grade: laboratory investigation.
Journal of neurosurgery - 1 Dec 2012
Lu Jie, Ksendzovsky Alexander, Yang Chunzhang, Mehta Gautam U, Yong Raymund L, Weil Robert J, Park Deric M, Mushlin Harry M, Fang Xueping, Balgley Brian M, Lee Dae-Hee, Lee Cheng S, Lonser Russell R, Zhuang Zhengping
Abstract excerpt
OBJECT: Tumor-initiating cells are uniquely resilient to current treatment modalities and play an important role in tumor resistance and recurrence. The lack of specific tumor-initiating cell markers to identify and target these cells presents a major obstacle to effective directed therapy. METHO...
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