Article
Epidermal growth factor receptor tyrosine kinase inhibitors beyond progressive disease: a retrospective analysis for Japanese patients with activating EGFR mutations.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Nov 2012
Nishie Kenichi, Kawaguchi Tomoya, Tamiya Akihiro, Mimori Tomoyasu, Takeuchi Naoko, Matsuda Yoshinobu, Omachi Naoki, Asami Kazuhiro, Okishio Kyoichi, Atagi Shinji, Okuma Tomohisa, Kubo Akihito, Maruyama Yoshihito, Kudoh Shinzoh, Takada Minoru
Abstract excerpt
INTRODUCTION: It is not determined whether the continuous use of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) is reasonable for patients with activating EGFR mutations, who have progressed with the drug. METHODS: We retrospectively analyzed the data from 2002 to 2010 of consecutive patients who had advanced non-small-cell lung cancer (NSCLC) harboring activating EGFR mutations and...
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