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Article

T790M mutation is associated with better efficacy of treatment beyond progression with EGFR-TKI in advanced NSCLC patients.

Lung cancer (Amsterdam, Netherlands) - 1 Jun 2014

Li Wei, Ren Shengxiang, Li Jiayu, Li Aiwu, Fan Lihong, Li Xuefei, Zhao Cao, He Yayi, Gao Guanghui, Chen Xiaoxia, Li Shuai, Shi Jingyun, Zhou Caicun, Fei Ke, Schmid-Bindert Gerald

Abstract excerpt

BACKGROUND AND PURPOSE: Continuous EGFR-TKI treatment beyond progression has shown promising benefit for some patients with acquired resistance to EGFR-TKIs. The aim of this study was to investigate the association of secondary T790M mutation at the time of progression with the efficacy of EGFR-T...

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Identifiers

PMID: 24685306
DOI: 10.1016/j.lungcan.2014.03.011

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24685306-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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