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Culture of oocytes and risk of imprinting defects

10 Oct 2012

Abstract excerpt

BACKROUND Follicle culture and oocyte in vitro maturation (IVM) are emerging assisted reproductive technologies with potentially important future applications in the fertility clinic. There is concern that these technologies might interfere at the epigenetic level and, in particular, with genomic imprinting. The timely acquisition of correct imprinting patterns in oocytes and the maintenance of genomic imprinting...

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Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
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PMID: 23054129
DOI: 10.1093/humupd/dms042

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