Article
Vitamin D receptor polymorphisms in hypertensive disorders of pregnancy.
Molecular biology reports - 1 Dec 2012
Rezende Vania B, Sandrim Valeria C, Palei Ana C, Machado Lorena, Cavalli Ricardo C, Duarte Geraldo, Tanus-Santos Jose E
Abstract excerpt
Hypertension is the most common medical disorder in pregnancy, and a leading cause of maternal and neonatal morbidity and mortality. Vitamin D endocrine system has important influence on immune modulation and endothelial function, which play a role in preeclampsia (PE) and gestational hypertension (GH). Vitamin D receptor (VDR) is present in a large variety of cell types, including placental cells. We examined...
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