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Article

Mental quality of life is related to a cytokine genetic pathway.

PloS one - 1 Jan 2012

Schoormans Dounya, Radonic Teodora, de Witte Piet, Groenink Maarten, Azim Donija, Lutter Rene, Mulder Barbara J M, Sprangers Mirjam A G, Zwinderman Aeilko H

Abstract excerpt

BACKGROUND: Quality of life (QoL) in patients with chronic disease is impaired and cannot be solely explained by disease severity. We explored whether genetic variability and activity contributes to QoL in patients with Marfan syndrome (MFS), a genetic connective tissue disorder. METHODOLOGY/PRINCIPAL FINDINGS: In 121 MFS patients, patient characteristics (i.e. demographics and MFS-related symptoms) were...

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Source

Open in PubMed Open full text

Identifiers

PMID: 23049769
DOI: 10.1371/journal.pone.0045126
PMCID: PMC3458023

Genes

CXCL11
CXCL9
CCL11
IFNA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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