Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Patient-specific protein aggregates in myofibrillar myopathies: laser microdissection and differential proteomics for identification of plaque components.

Proteomics - 1 Dec 2012

Feldkirchner Sarah, Schessl Joachim, Müller Stefan, Schoser Benedikt, Hanisch Franz-Georg

Abstract excerpt

Myofibrillar myopathies (MFMs) are histopathologically characterized by desmin-positive protein aggregates and myofibrillar degeneration. While about half of all MFM are caused by mutations in genes encoding sarcomeric and extra-sarcomeric proteins (desmin, filamin C, plectin, VCP, FHL1, ZASP, my...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Laser Capture Microdissection
Share to Muscle, Skeletal
Share to Muscular Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Proteome

Share to Proteomics

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Share to Staining and Labeling

Source

Identifiers

PMID: 23044792
DOI: 10.1002/pmic.201100559

Genes

FHL1
BAG3
NRAP
RTN2
VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23044792-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Patient-specific protein aggregates in myofibrillar myopathies: laser microdissection and differential proteomics for identification of plaque components.PMID 23044792Read ↗

A combined laser microdissection and mass spectrometry approach reveals new disease relevant proteins accumulating in aggregates of filaminopathy patients.Semantic proximity Read ↗

Myofibrillar Myopathies: A Clinical and Myopathological GuideSemantic proximity Read ↗

Molecular pathology of myofibrillar myopathies.Semantic proximity Read ↗

Proteomic characterization of aggregate components in an intrafamilial variable FHL1-associated myopathy.Semantic proximity Read ↗

New aspects of myofibrillar myopathies.Semantic proximity Read ↗

Histopathology of Duchenne muscular dystrophy in correlation with changes in proteomic biomarkers.Semantic proximity Read ↗

Emerging proteomic biomarkers of X-linked muscular dystrophySemantic proximity Read ↗

Differential proteomic analysis of abnormal intramyoplasmic aggregates in desminopathy.Semantic proximity Read ↗

Myofibrillar myopathy in the genomic context.Semantic proximity Read ↗

Proteomic identification of FHL1 as the protein mutated in human reducing body myopathy.Semantic proximity Read ↗

FLNC-Associated Myofibrillar MyopathySemantic proximity Read ↗

New insights into the protein aggregation pathology in myotilinopathy by combined proteomic and immunolocalization analyses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.