Article
Laminin-1 (LM-111) in preeclampsia and systemic lupus erythematosus.
Autoimmunity - 1 Feb 2013
Páez Maria-Carolina, Matsuura Eiji, Díaz Luis A, Shoenfeld Yehuda, Serrano Norma C, Anaya Juan-Manuel
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of antibodies. SLE has been associated with placental pathology, a finding that is also the determinant in preeclampsia (PE). Genetic evidence and serologic reports suggest laminin-1 (LM-111) as an immunogenic molecule and its polymorphic gene as a candidate gene for both disorders. OBJECTIVE: To evaluate the...
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