Article
Effects of the apolipoprotein E polymorphism on uptake and transfer of cell-derived cholesterol in plasma.
The Journal of clinical investigation - 1 Dec 1995
Huang Y, von Eckardstein A, Wu S, Assmann G
Abstract excerpt
The reverse cholesterol transport is initiated by the uptake of cholesterol into minor subfractions of high density lipoproteins (HDL) which contain either apolipoprotein (apo) A-I or apoE as their only apolipoproteins. From these initial acceptors, which are termed prebeta1-LpA-I and gamma-LpE, respectively, cell-derived cholesterol is transferred to LDL via the bulk of HDL termed alpha-LpA-I. In this study we...
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