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Article

An evolutionary link between natural transformation and CRISPR adaptive immunity.

mBio - 1 Jan 2012

Jorth Peter, Whiteley Marvin

Abstract excerpt

UNLABELLED: Natural transformation by competent bacteria is a primary means of horizontal gene transfer; however, evidence that competence drives bacterial diversity and evolution has remained elusive. To test this theory, we used a retrospective comparative genomic approach to analyze the evolutionary history of Aggregatibacter actinomycetemcomitans, a bacterial species with both competent and noncompetent...

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Topics

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Share to Evolution, Molecular
Share to Gene Transfer, Horizontal
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Bacterial

Share to Host Specificity

Share to Recombination, Genetic

Share to Transformation, Genetic

Source

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Identifiers

PMID: 23033473
DOI: 10.1128/mBio.00309-12
PMCID: PMC3484387

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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