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Article

The Arms Race Between Actinobacillus pleuropneumoniae and Its Genetic Environment: A Comprehensive Analysis of Its Defensome and Mobile Genetic Elements.

Molecular microbiology - 1 Jul 2025

da Silva Giarlã Cunha, Rossi Ciro César

Abstract excerpt

Actinobacillus pleuropneumoniae is the causative agent of pleuropneumonia in swine, a highly contagious and economically significant disease. The genetic variability of A. pleuropneumoniae complicates disease control efforts, as it enables rapid adaptation to various stressors, including antimicrobial treatments. To better understand the molecular mechanisms underlying this adaptability, we investigated the role...

Read the complete abstract on PubMed

Topics

Actinobacillus pleuropneumoniae
Interspersed Repetitive Sequences
Prophages
Swine
Animals
Plasmids

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

CRISPR-Cas Systems

Genetic Variation

Swine Diseases

Genome, Bacterial

Actinobacillus Infections

Computational Biology

Source

Open in PubMed Open full text

Identifiers

PMID: 40317571
DOI: 10.1111/mmi.15374
PMCID: PMC12242098

Provenance

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