Article
Characterization of serotonin transporter gene (SLC6A4) polymorphisms and its association with drug dependence in a Jordanian Arab population.
Toxicology and industrial health - 1 Aug 2014
Al-Eitan Laith Naser, Jaradat Saied Ali, Qin Wenwen, Wildenauer Diah Mutiara B, Wildenauer Dieter D B, Hulse Gary K, Tay Guan K
Abstract excerpt
Drug dependence is a pattern of repeated self-administration of a drug, which can result in tolerance, withdrawal and compulsive drug-taking behaviour. It has been recently suggested that 5-HTTLPR (LL/LS/SS) variants and rs25531 (A/G) polymorphism in the serotonin transporter gene (SLC6A4) may play a role in drug dependence. The current study aimed to (1) identify allelic, haplotypic and genotypic frequencies of...
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