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Article

Getting personal: understanding how genetic variation affects clinical outcomes in patients with tetralogy of Fallot.

Pediatric research - 1 Oct 2012

Russell Mark W, Wilder Nicole S

Abstract excerpt

The work by Jeewa et al. is an important step toward “personalizing” or individualizing our approach to care of patients with tetralogy of Fallot. Although future studies will need to confirm the potential role of HIF1A-mediated signaling in right ventricular remodeling, it raises the possibility that modulation of the HIF1A signaling pathway or its downstream effectors such as TGF-β may allow better preservation...

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Share to Cardiac Surgical Procedures
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Share to Hypoxia-Inducible Factor 1, alpha Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 23032507
DOI: 10.1038/pr.2012.104
PMCID: PMC3576875

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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