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Article

Peripheral PDLIM5 expression in bipolar disorder and the effect of olanzapine administration.

BMC medical genetics - 2 Oct 2012

Zain Mohd Aizat, Jahan Suffee Nusrat, Reynolds Gavin P, Zainal Nor Zuraida, Kanagasundram Sharmilla, Mohamed Zahurin

Abstract excerpt

BACKGROUND: One of the genes suggested to play an important role in the pathophysiology of bipolar disorder (BPD) is PDLIM5, which encodes LIM domain protein. Our main objective was to examine the effect of olanzapine treatment on PDLIM5 mRNA expression in the peripheral blood leukocytes of BPD patients. METHODS: We measured the expression of PDLIM5 mRNA from 16 patients with BPD Type I after 0, 4, and 8 weeks of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23031404
DOI: 10.1186/1471-2350-13-91
PMCID: PMC3502145

Genes

PDLIM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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