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Article

Enhancement of immune response induced by <scp>DNA</scp> vaccine cocktail expressing complete <scp>LACK</scp> and <scp>TSA</scp> genes against <i>Leishmania major</i>

18 Sept 2012

Abstract excerpt

Leishmaniasis is an important disease in humans. Leishmania homologue of receptor for Activated C Kinase (LACK) and thiol specific antioxidant (TSA) as immuno-dominant antigens of Leishmania major are considered the most promising molecules for a DNA vaccine. We constructed a DNA cocktail, containing plasmids encoding LACK and TSA genes of Leishmania major and evaluated the immune response and survival rate in...

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PMID: 23030526
DOI: 10.1111/j.1600-0463.2012.02968.x

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