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Article

Mutational analysis of the respiratory nitrate transporter NarK2 of Mycobacterium tuberculosis.

PloS one - 1 Jan 2012

Giffin Michelle M, Raab Ronald W, Morganstern Melissa, Sohaskey Charles D

Abstract excerpt

Mycobacterium tuberculosis induces nitrate reductase activity in response to decreasing oxygen levels. This is due to regulation of both the transcription and the activity of the nitrate transporter NarK2. A model of NarK2 structure is proposed containing 12 membrane spanning regions consistent with other members of the major facilitator superfamily. The role of the proton gradient was determined by exposing M....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23029022
DOI: 10.1371/journal.pone.0045459
PMCID: PMC3445494

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