Article
Clonal analysis in the ultrastructure of cell-to-cell interaction between a human glioma cell line and autologous tumor-specific cytotoxic T lymphocytes.
Cellular immunology - 1 Mar 1990
Iwasaki K, Kikuchi H, Miyatake S, Oda Y, Yamashita J, Yamasaki T
Abstract excerpt
The clonal analysis in the ultrastructure of tumor-lymphocyte interaction was carried out in order to investigate the precise mechanism responsible for CTL-mediated cytolysis of tumor cells. A glioma-derived cell line (GI-1) and autologous tumor-specific cytotoxic T lymphocyte (CTL) clones were e...
Topics
- Cell Communication
- Clone Cells
- Cytoplasmic Granules
- Cytotoxicity, Immunologic
- Glioma
- Humans
- Microscopy, Electron
- Monensin
- Phenotype
- T-Lymphocytes, Cytotoxic
- Tumor Cells, Cultured