Article
Electron microscopic observation of killer cells induced by mixed culture of lymphocytes with autologous cancer cells and further culture with recombinant interleukin-2.
Auris, nasus, larynx - 1 Jan 1992
Murakami H, Matsuoka H, Fukiage T, Samejima Y, Eura M, Ikawa T, Ishikawa T, Kanda T
Abstract excerpt
Peripheral blood lymphocytes obtained from 2 patients with hypopharyngeal cancer were cultured with mitomycin C treated autologous tumor cells (autologous MLTC) for 10 days and further cultured with recombinant interleukin 2 (rIL-2). In one case 10-day MLTC induced increase of CD25-positive lymphocyte count, indicating that IL-2 receptors were expressed dominantly by the autologous tumor stimulation, and further...
Topics
- Antigens, CD
- Cells, Cultured
- Culture Media, Conditioned
- Cytotoxicity, Immunologic
- Humans
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Killer Cells, Natural
- Lymphocytes
- Microscopy, Electron