Article
The PmrAB system-inducing conditions control both lipid A remodeling and O-antigen length distribution, influencing the Salmonella Typhimurium-host interactions.
The Journal of biological chemistry - 9 Nov 2012
Farizano Juan V, Pescaretti María de las Mercedes, López Fabián E, Hsu Fong-Fu, Delgado Mónica A
Abstract excerpt
The Salmonella enterica serovar Typhimurium lipopolysaccharide consisting of covalently linked lipid A, non-repeating core oligosaccharide, and the O-antigen polysaccharide is the most exposed component of the cell envelope. Previous studies demonstrated that all of these regions act against the host immunity barrier. The aim of this study was to define the role and interaction of PmrAB-dependent gene products...
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