Article
Impact of gag genetic determinants on virological outcome to boosted lopinavir-containing regimen in HIV-2-infected patients.
AIDS (London, England) - 2 Jan 2013
Larrouy Lucile, Vivot Alexandre, Charpentier Charlotte, Bénard Antoine, Visseaux Benoit, Damond Florence, Matheron Sophie, Chene Geneviève, Brun-Vezinet Françoise, Descamps Diane
Abstract excerpt
OBJECTIVE: This study investigated the impact on virological outcome of the gag cleavage sites and the protease-coding region mutations in protease inhibitor-naive and protease inhibitor-experienced patients infected with HIV-2 receiving lopinavir (LPV) containing regimen. METHODS: Baseline gag and protease-coding region were sequenced in 46 HIV-2 group A-infected patients receiving lopinavir. Virological...
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