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Article

Low expression level of phosphatase and tensin homolog deleted on chromosome ten predicts poor prognosis in chronic lymphocytic leukemia.

Leukemia & lymphoma - 1 Jun 2013

Zou Zhi-Jian, Zhang Run, Fan Lei, Wang Li, Fang Cheng, Zhang Li-Na, Yang Shu, Li Yuan-Yuan, Li Jian-Yong, Xu Wei

Abstract excerpt

Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is one of the best-studied tumor suppressor genes which can promote cell proliferation and contribute to tumorigenesis. This study aimed to investigate the PTEN mRNA (Pm) expression level in patients with chronic lymphocytic leukemia (CLL) and healthy controls, and its correlation with prognostic factors. Quantitative polymerase chain reaction (qPCR)...

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Share to Aged, 80 and over
Share to Gene Expression Regulation, Leukemic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Share to PTEN Phosphohydrolase

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Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 23013295
DOI: 10.3109/10428194.2012.733880

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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