Article
The possibility of mutations of RAS signaling genes and/or TP53 in combination as a negative prognostic impact on pathological stage I non-small cell lung cancer.
Cancer medicine - 1 Oct 2023
Honda Takayuki, Seto Katsutoshi, Endo Satoshi, Takemoto Akira, Tanimoto Kousuke, Kobayashi Masashi, Kitano Masatake, Sakakibara Rie, Mitsumura Takahiro, Ishibashi Hironori, Inazawa Johji, Tanaka Toshihiro, Miyazaki Yasunari, Okubo Kenichi
Abstract excerpt
BACKGROUND: The recurrence rate of non-small cell lung cancer (NSCLC) is as high as 30%, even in the cancer with pathological stage I disease. Therefore, identifying factors predictive of high-risk pathological recurrence is important. However, few studies have examined the genetic status of these tumors and its relationship to prognosis. MATERIALS AND METHODS: A cohort of 328 cases of primary lung cancer that...
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