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Article

Increased knowledge of Francisella genus diversity highlights the benefits of optimised DNA-based assays.

BMC microbiology - 25 Sept 2012

Ahlinder Jon, Öhrman Caroline, Svensson Kerstin, Lindgren Petter, Johansson Anders, Forsman Mats, Larsson Pär, Sjödin Andreas

Abstract excerpt

BACKGROUND: Recent advances in sequencing technologies offer promising tools for generating large numbers of genomes, larger typing databases and improved mapping of environmental bacterial diversity. However, DNA-based methods for the detection of Francisella were developed with limited knowledge about genetic diversity. This, together with the high sequence identity between several Francisella species, means...

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PMID: 23009728
DOI: 10.1186/1471-2180-12-220
PMCID: PMC3575276

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