Article
General theory of genotype to phenotype mapping: derivation of epigenetic landscapes from N-node complex gene regulatory networks.
Physical review letters - 14 Sept 2012
Villarreal Carlos, Padilla-Longoria Pablo, Alvarez-Buylla Elena R
Abstract excerpt
We propose a systematic methodology to construct a probabilistic epigenetic landscape of cell-fate attainment associated with N-node Boolean genetic regulatory networks. The general derivation proposed here is exemplified with an Arabidopsis thaliana network underlying floral organ determination...
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