Article
Phosphoribosyl pyrophosphate synthetase, as a suppressor of the sepH mutation in Aspergillus nidulans, is required for the proper timing of septation.
Molecular microbiology - 1 Nov 2012
Zhong Guowei, Wei Wenfan, Guan Qi, Ma Zhaofei, Wei Hua, Xu Xushi, Zhang Shizhu, Lu Ling
Abstract excerpt
Timely cytokinesis/septation is essential for hyphal growth and conidiation in Aspergillus nidulans. Genetic analyses have identified that A. nidulans has components of the septum initiation network (SIN) pathway; one of these, SEPH, is a key player for early events during cytokinesis. However, little is known about how the SEPH kinase cascade is regulated by other components. Here, we demonstrate that the...
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