Article
A high throughput and sensitive method correlates neuronal disorder genotypes to Drosophila larvae crawling phenotypes.
Fly - 1 Jan 2000
Jakubowski Brandon R, Longoria Rafael A, Shubeita George T
Abstract excerpt
Drosophila melanogaster is widely used as a model system for development and disease. Due to the homology between Drosophila and human genes, as well as the tractable genetics of the fly, its use as a model for neurologic disorders, in particular, has been rising. Locomotive impairment is a commonly used diagnostic for screening and characterization of these models, yet a fast, sensitive and model-free method to...
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