Article
Antitumor activity of motesanib alone and in combination with cisplatin or docetaxel in multiple human non-small-cell lung cancer xenograft models.
Molecular cancer - 19 Sept 2012
Coxon Angela, Ziegler Beth, Kaufman Stephen, Xu Man, Wang Hongyu, Weishuhn Dawn, Schmidt Joanna, Sweet Heather, Starnes Charlie, Saffran Douglas, Polverino Anthony
Abstract excerpt
BACKGROUND: Non-small-cell lung cancer (NSCLC) is categorized into various histologic subtypes that play an important role in prognosis and treatment outcome. We investigated the antitumor activity of motesanib, a selective antagonist of vascular endothelial growth factor receptors (VEGFR) 1, 2,...
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