Article
Efficacy of nintedanib plus docetaxel in patients with refractory advanced epidermal growth factor receptor mutant lung adenocarcinoma.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Dec 2021
Riudavets Mariona, Bosch-Barrera Joaquim, Cabezón-Gutiérrez Luís, Diz Taín Pilar, Hernández Ainhoa, Alonso Miriam, Blanco Remei, Gálvez Elisa, Insa Amelia, Mielgo Xabier, Morán Teresa, Ponce Santiago, Roa Diana, Sánchez José Miguel, Majem Margarita
Abstract excerpt
BACKGROUND: Anti-angiogenic agents are reported to exert clinical activity in patients with epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC). We evaluated the outcomes of the combination of docetaxel plus nintedanib in refractory NSCLC patients harboring EGFR mutations. METHODS: We retrospectively analyzed 19 patients with advanced EGFR-mutant NSCLC who had progressed to EGFR...
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