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Marking the markers of Alzheimer's: too good to diagnose, too bad to use?

Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology - 1 Sept 2012

Olah Zita, Pakaski Magdolna, Janka Zoltan, Kalman Janos

Abstract excerpt

One of the most important neurodegenerative diseases of our time is Alzheimer's disease, which mainly affects the elderly population. The accumulation of β-amyloid and tau protein in the brain tissue is the most characteristic pathomechanical event of the disease, later causing neuronal cell death. Setting up an accurate diagnosis of Alzheimer's disease has essentially changed recently, since besides psychometry,...

Topics

Age of Onset
Alzheimer Disease
Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Biomarkers
Brain
Cognitive Dysfunction
Diagnosis, Differential
Humans
Memory Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neuroimaging

Phosphorylation

Presenilin-1

Presenilin-2

Sensitivity and Specificity

tau Proteins

Source

Identifiers

PMID: 22987730

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