Article
The Saccharomyces cerevisiae W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt.
Open biology - 1 Aug 2012
Ralser Markus, Kuhl Heiner, Ralser Meryem, Werber Martin, Lehrach Hans, Breitenbach Michael, Timmermann Bernd
Abstract excerpt
Saccharomyces cerevisiae strain W303 is a widely used model organism. However, little is known about its genetic origins, as it was created in the 1970s from crossing yeast strains of uncertain genealogy. To obtain insights into its ancestry and physiology, we sequenced the genome of its variant W303-K6001, a yeast model of ageing research. The combination of two next-generation sequencing (NGS) technologies...
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