Article
IGF receptor gene variants in normal adolescents: effect on stature.
European journal of endocrinology - 1 Dec 2012
Kansra Alvina R, Dolan Lawrence M, Martin Lisa J, Deka Ranjan, Chernausek Steven D
Abstract excerpt
OBJECTIVE: IGF1 is essential for human growth and mediates its effects through the type 1 IGF receptor (IGF1R). Our objective was to determine the frequency of certain previously reported IGF1R gene variants in the normal population and their effect on stature. DESIGN: A cross-sectional study was conducted in a population of 2500 children enrolled in public school grades 5 through 12 for whom DNA and...
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