Article
Vitiligo is associated with HLA-DR4 in black patients. A preliminary report.
Archives of dermatology - 1 Jan 1990
Dunston G M, Halder R M
Abstract excerpt
We have determined the HLA-DR and HLA-DQ phenotypes of 24 black patients with vitiligo and compared these with phenotypes of 143 local black controls. HLA-DR4 was significantly increased in patients, 38% vs 11% for controls. HLA-DQw3 was also increased in patients, 58% vs 32% for controls and may be explained in part by linkage disequilibrium with HLA-DR4. When patients were subgrouped according to family history...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Black People
- Disease Susceptibility
- Female
- HLA-DQ Antigens
- HLA-DR4 Antigen
- HLA-DR6 Antigen
- Heterozygote
- Homozygote
