Article
Asthma phenotyping, therapy, and prevention: what can we learn from systems biology?
Pediatric research - 1 Apr 2013
Sittka Alexandra, Vera Julio, Lai Xin, Schmeck Bernd T
Abstract excerpt
Asthma has a high prevalence worldwide, and contributes significantly to the socioeconomic burden. According to a classical paradigm, asthma symptoms are attributable to an allergic, Th2-driven airway inflammation that causes airway hyperresponsiveness and results in reversible airway obstruction. Diagnosis and therapy are based mainly on these pathophysiologic concepts. However, these have increasingly been...
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