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Article

A novel classification framework for genome-wide association study of whole brain MRI images using deep learning.

PLoS computational biology - 1 Oct 2024

Yu Shaojun, Wu Junjie, Shao Yumeng, Qiu Deqiang, Qin Zhaohui S

Abstract excerpt

Genome-wide association studies (GWASs) have been widely applied in the neuroimaging field to discover genetic variants associated with brain-related traits. So far, almost all GWASs conducted in neuroimaging genetics are performed on univariate quantitative features summarized from brain images. On the other hand, powerful deep learning technologies have dramatically improved our ability to classify images. In...

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PMID: 39405331
DOI: 10.1371/journal.pcbi.1012527
PMCID: PMC11508069

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