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Human leukocyte antigen-C and killer cell immunoglobulin-like receptor gene polymorphisms among patients with syphilis in a Chinese Han population.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Oct 2012

Zhuang Yun-Long, Ren Gui-Jie, Tian Ke-Li, Li Xin-Ye, Zhu Yong-Bao, Liu Jin-Ling, Si Gui-Ling, Li Peng, Zhang Yi, Wang Li, Zhang Wen-Jing, Wang Da-Jian, Zhu Chuan-Fu

Abstract excerpt

Syphilis is a sexually transmitted infection caused by the Treponema pallidum subspecies pallidum spirochete bacterium. The killer cell immunoglobulin-like receptors (KIR), interacting with human leukocyte antigens (HLA), regulate the activations of natural killer (NK) cells and certain T-cell subsets in response to microbe infection. The objective of this study was to explore whether KIR and HLA-C gene...

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Identifiers

PMID: 22958291
DOI: 10.1111/j.1600-0463.2012.02911.x

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