Article
Evolution of simple sequence repeat-mediated phase variation in bacterial genomes.
Annals of the New York Academy of Sciences - 1 Sept 2012
Bayliss Christopher D, Palmer Michael E
Abstract excerpt
Mutability as mechanism for rapid adaptation to environmental challenge is an alluringly simple concept whose apotheosis is realized in simple sequence repeats (SSR). Bacterial genomes of several species contain SSRs with a proven role in adaptation to environmental fluctuations. SSRs are hypermutable and generate reversible mutations in localized regions of bacterial genomes, leading to phase variable ON/OFF...
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