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Article

Association between estrogen receptor-β dinucleotide repeat polymorphism and incidence of femoral fracture.

Journal of bone and mineral metabolism - 1 Jan 2013

Honma Naoko, Mori Seijiro, Zhou Heying, Ikeda Shinobu, Mieno Makiko Naka, Tanaka Noriko, Takubo Kaiyo, Arai Tomio, Sawabe Motoji, Muramatsu Masaaki, Ito Hideki

Abstract excerpt

Estrogens are thought to play an important role in bone metabolism through estrogen receptors (ER). Dinucleotide (cytosine-adenine, CA) repeat polymorphism in the human ER-β gene (ESR2) has been reported to be associated with bone mineral density. We aimed to further elucidate the importance of this polymorphism in the pathogenesis of osteoporosis by examining its association with the incidence of femoral...

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PMID: 22948905
DOI: 10.1007/s00774-012-0383-z

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ESR2

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