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Article

Association of estrogen receptor dinucleotide repeat polymorphism with osteoporosis.

Biochemical and biophysical research communications - 5 Dec 1995

Sano M, Inoue S, Hosoi T, Ouchi Y, Emi M, Shiraki M, Orimo H

Abstract excerpt

We investigated the association between dinucleotide (thymine-adenine) repeat polymorphism lying upstream of human estrogen receptor (ER) gene and bone mineral density (BMD) as well as biochemical markers for bone metabolism in 144 healthy postmenopausal Japanese women. The genotype was classified into 'A' through 'R' according to the number of the repeats, from 10 to 27. BMD was expressed in Z score (a deviation...

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PMID: 8526937
DOI: 10.1006/bbrc.1995.2787

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