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Article

Brachial artery occlusion in a young adult with an ACTA2 thoracic aortic aneurysm.

Vascular medicine (London, England) - 1 Oct 2012

Al-Mohaissen Maha, Allanson Judith E, O'Connor Michael D, Veinot John P, Brandys Timothy M, Maharajh Gyaandeo, Dennie Carole J, Beauchesne Luc M

Abstract excerpt

Mutations of the ACTA2 gene, which encodes the smooth muscle cell-specific isoform of α-actin protein, have recently been found to be among the most common genetic abnormalities observed in patients with familial thoracic aortic aneurysms/dissection (TAAD). Other reported vascular manifestations caused by these mutations include premature coronary artery disease and stroke. We report a young adult who presented...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22946110
DOI: 10.1177/1358863X12453973

Genes

ACTA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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