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Article

Clinical outcomes of aortic repair in young adult patients with ACTA2 mutations.

General thoracic and cardiovascular surgery - 1 Dec 2017

Seike Yoshimasa, Minatoya Kenji, Sasaki Hiroaki, Tanaka Hiroshi, Itonaga Tatsuya, Inoue Yosuke, Morisaki Hiroko, Morisaki Takayuki, Ishibashi-Ueda Hatsue, Kobayashi Junjiro

Abstract excerpt

OBJECTIVES: Actin, alpha-2, smooth muscle, aorta (ACTA2) mutations are one of the major causes of familial thoracic aortic aneurysms and dissections. The aim of this study was to review our clinical results of young adult patients with aortic disease caused by ACTA2 mutations. METHODS: We reviewed the medical records of 251 patients (<50 years old) who underwent surgery for thoracic aortic diseases between 2004...

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Identifiers

PMID: 28808903
DOI: 10.1007/s11748-017-0810-0

Genes

ACTA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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