Article
Lack of association between two key SNPs on chromosome 12p13 and ischemic stroke in Chinese Uyghur population.
Journal of the neurological sciences - 15 Dec 2012
Tong Yeqing, Zhan Faxian, Han Jinjun, Zhang Yanwei, Yin Xiaoxu, Geng Yijie, Hou Shuangyi, Ye Jianjun, Guan Xuhua, Han Shenhong, Wang Yunxia, Mason Katherine A, Lu Zuxun, Liu Jiafa, Cheng Jinquan
Abstract excerpt
Recent genome-wide association studies (GWAS) have identified two key SNPs (rs11833579 and rs12425791) on chromosome 12p13 that were significantly associated with stroke in Caucasians. However, the validity of the association has remained controversial. We performed genetic association analyses in a very unique population which has 60% European ancestry and 40% East Asian ancestry. No significant association...
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