Article
Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.
Journal of human genetics - 1 Jul 2010
Matsushita Tomonaga, Umeno Junji, Hirakawa Yoichiro, Yonemoto Koji, Ashikawa Kyota, Amitani Hanae, Ninomiya Toshiharu, Hata Jun, Doi Yasufumi, Kitazono Takanari, Iida Mitsuo, Nakamura Yusuke, Kiyohara Yutaka, Kubo Michiaki
Abstract excerpt
Recent genome-wide association study using four prospective population-based cohorts identified two single-nucleotide polymorphisms (SNPs) on chromosome 12p13, rs12425791 and rs11833579, to be significantly associated with the incidence of atherothrombotic stroke. To examine the association of these SNPs with atherothrombotic stroke in the Japanese population, we carried out a case-control association study using...
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