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Article

Predictive role of ERCC1 and XPD genetic polymorphisms in survival of Chinese non-small cell lung cancer patients receiving chemotherapy.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Zhang Zhen-Yong, Tian Xin, Wu Rong, Liang Yuan, Jin Xue-Ying

Abstract excerpt

AIM: There is increasing evidence that ERCC1 and XPD have roles in response to chemotherapy among patients with NSCLC, but the results are conflicting. Therefore, we conducted the present prospective study in a Chinese population. METHODS: A total of 632 primary NSCLC patients were included, followed-up from May 2006 to May 2011. Polymorphisms were detected by real time PCR with TaqMan probse, using genomic DNA...

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Identifiers

PMID: 22938424
DOI: 10.7314/apjcp.2012.13.6.2583

Genes

ERCC1

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