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Article

A primary reduced TCA flux governs substrate oxidation in T2D skeletal muscle.

Current diabetes reviews - 1 Nov 2012

Gaster Michael

Abstract excerpt

Our current knowledge on substrate oxidation in skeletal muscle in relation to insulin resistance and type 2 diabetes (T2D) originate mainly from in vivo studies. The oxidative capacity of skeletal muscle is highly influenced by physical activity, ageing, hormonal status, and fiber type composition, rendering it difficult to determine the contribution of heritable factors to the alteration in oxidative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22934552
DOI: 10.2174/157339912803529841

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