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Article

Russian "successful" clone B0/W148 of Mycobacterium tuberculosis Beijing genotype: a multiplex PCR assay for rapid detection and global screening.

Journal of clinical microbiology - 1 Nov 2012

Mokrousov Igor, Narvskaya Olga, Vyazovaya Anna, Otten Tatiana, Jiao Wei-Wei, Gomes Lia Lima, Suffys Philip N, Shen A-Dong, Vishnevsky Boris

Abstract excerpt

We describe a multiplex PCR assay to detect the Mycobacterium tuberculosis Beijing genotype variant B0/W148, which is considered a "successful" clone of M. tuberculosis, widespread in Russia. Specificity and sensitivity of the assay were 100% based on the analysis of a collection of 516 M. tuberculosis isolates of different genotypes and origins. This assay may be used for accurate and simple detection and...

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Identifiers

PMID: 22933595
DOI: 10.1128/JCM.02001-12
PMCID: PMC3486266

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