Article
Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.
Development (Cambridge, England) - 1 Nov 2012
Vijayaraj Preethi, Le Bras Alexandra, Mitchell Nora, Kondo Maiko, Juliao Saul, Wasserman Meredith, Beeler David, Spokes Katherine, Aird William C, Baldwin H Scott, Oettgen Peter
Abstract excerpt
During murine embryogenesis, the Ets factor Erg is highly expressed in endothelial cells of the developing vasculature and in articular chondrocytes of developing bone. We identified seven isoforms for the mouse Erg gene. Four share a common translational start site encoded by exon 3 (Ex3) and are enriched in chondrocytes. The other three have a separate translational start site encoded by Ex4 and are enriched in...
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